1-[3-(trifluoromethyl)phenyl]cyclobutane-1-carboxylic acid is an organic compound with the chemical formula C13H11F3O2.
Nature:
1-[3-(trifluoromethyl)phenyl]cyclobutane-1-carboxylic acid is a solid with colorless to pale yellow crystals. It is stable at room temperature and soluble in some organic solvents such as methylene chloride and dimethyl sulfoxide.
Use:
1-[3-(trifluoromethyl)phenyl]cyclobutane-1-carboxylic acid is commonly used as an intermediate in organic synthesis. It can be used to prepare drugs, pesticides and chemical reagents.
Method:
1-[3-(trifluoromethyl)phenyl]cyclobutane-1-carboxylic acid can be prepared by several synthetic routes. A commonly used method is to use phenylacetylene and trifluoromethylbenzoic acid as raw materials, add reaction under appropriate conditions, and then carry out acid hydrolysis reaction to obtain the target product.